Ectolysins Against Gram Positive Bacterial Infections

Ectolysins against Staphylococcus

Ectolysin P128, GangaGen’s lead molecule is a chimeric recombinant anti-staphylococcal protein that targets both coagulase positive and coagulase negative Staphylococci.

P128 has a novel mechanism of action and rapidly kills Staphylococci.

It is proven to be very effective both in vitro & in vivo against multidrug resistant pathogens like Methicillin Resistant Staphylococcus aureus (MRSA), Vancomycin Resistant Staphylococcus aureus (VRSA) and Daptomycin Resistant Staphylococcus aureus (DRSA). GangaGen has completed Phase I/IIA studies with P128 for ‘nasal decontamination of S. aureus from human nares.

Ectolysins against Enterococcus

GangaGen has used PATP to discover and engineer novel ectolysins suitable for multiple applications.

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